Article
Low prevalence of primary antiretroviral resistance mutations and predominance of HIV-1 clade C at polymerase gene in newly diagnosed individuals from south Brazil.
Virus research - 1 Mar 2006
Rodrigues Rosangela, Scherer Luciene C, Oliveira Cristina M, Franco Heitor Moreira, Sperhacke Rosa Dea, Ferreira Joao Leandro Paula, Castro Simone Martins, Stella Isete Maria, Brigido Luis Fernando Macedo
Abstract excerpt
We describe preliminary molecular characterization of HIV-1 pol from 108 consecutive HIV seropositive users of a Voluntary Counseling and Testing (VCT) site of Porto Alegre city, the major metropolitan area in the south of Brazil. Protease and partial reverse transcriptase regions were retrotranscribed from plasma HIV-1 RNA and sequenced after direct nested PCR. Principal antiretroviral resistance mutations (ARM)...
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