Article
Determinants of the streptococcal surface glycoprotein GspB that facilitate export by the accessory Sec system.
Molecular microbiology - 1 Dec 2005
Bensing Barbara A, Takamatsu Daisuke, Sullam Paul M
Abstract excerpt
GspB is a large cell-surface glycoprotein expressed by Streptococcus gordonii M99 that mediates binding of this organism to human platelets. This adhesin is glycosylated in the cytoplasm, and is then transported to the cell surface via an accessory Sec system. To assess the structural features of GspB that are needed for export, we examined the effects of altering the carbohydrate moieties or the polypeptide...
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