Article
Cytogenetic and molecular evaluation of 241 small supernumerary marker chromosomes: cooperative study of 19 Italian laboratories.
Genetics in medicine : official journal of the American College of Medical Genetics - 1 Jan 2000
Dalprà Leda, Giardino Daniela, Finelli Palma, Corti Cecilia, Valtorta Chiara, Guerneri Silvana, Ilardi Patrizia, Fortuna Renato, Coviello Domenico, Nocera Gianfranco, Amico Francesco Paolo, Martinoli Emanuela, Sala Elena, Villa Nicoletta, Crosti Francesca, Chiodo Francamaria, di Cantogno Ludovica Verdun, Savin Elisa, Croci Gianfranco, Franchi Fabrizia, Venti Giovanna, Donti Emilio, Migliori Valeria, Pettinari Antonella, Bonifacio Stefania, Centrone Claudia, Torricelli Francesca, Rossi Simona, Simi Paolo, Granata Paola, Casalone Rosario, Lenzini Elisabetta, Artifoni Lina, Pecile Vanna, Barlati Sergio, Bellotti Daniela, Caufin Daniele, Police Adalgisa, Cavani Simona, Piombo Giuseppe, Pierluigi Mauro, Larizza Lidia
Abstract excerpt
PURPOSE: We evaluated the experiences of 19 Italian laboratories concerning 241 small supernumerary marker chromosomes (sSMCs) with the aim of answering questions arising from their origin from any chromosome, their variable size and genetic content, and their impact on the carrier's phenotype. METHODS: Conventional protocols were used to set up the cultures and chromosome preparations. Both commercial and...
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