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Article

Azurin of pathogenic Neisseria spp. is involved in defense against hydrogen peroxide and survival within cervical epithelial cells.

Infection and immunity - 1 Dec 2005

Wu Hsing-Ju, Seib Kate L, Edwards Jennifer L, Apicella Michael A, McEwan Alastair G, Jennings Michael P

Abstract excerpt

Laz, a lipid-modified azurin of the human pathogens Neisseria gonorrhoeae and Neisseria meningitidis, is involved in defense against oxidative stress and copper toxicity; laz mutant strains are hypersensitive to hydrogen peroxide and copper. The N. gonorrhoeae laz mutant also has decreased survival in an ex vivo primary human ectocervical epithelial assay.

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Source

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Identifiers

PMID: 16299348
DOI: 10.1128/IAI.73.12.8444-8448.2005
PMCID: PMC1307039

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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