Article
Identification of core and variable components of the Salmonella enterica subspecies I genome by microarray.
Infection and immunity - 1 Dec 2005
Anjum Muna F, Marooney Chris, Fookes Maria, Baker Stephen, Dougan Gordon, Ivens Al, Woodward Martin J
Abstract excerpt
We have performed microarray hybridization studies on 40 clinical isolates from 12 common serovars within Salmonella enterica subspecies I to identify the conserved chromosomal gene pool. We were able to separate the core invariant portion of the genome by a novel mathematical approach using a decision tree based on genes ranked by increasing variance. All genes within the core component were confirmed using...
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