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Article

Characterization of an aldolase-binding site in the Wiskott-Aldrich syndrome protein.

The Journal of biological chemistry - 20 Jan 2006

Buscaglia Carlos A, Penesetti Deepak, Tao Mingyuan, Nussenzweig Victor

Abstract excerpt

The thrombospondin-related anonymous protein (TRAP) is an essential transmembrane molecule in Plasmodium sporozoites. TRAP displays adhesive motifs on the extracellular portion, whereas its cytoplasmic tail connects to actin via aldolase, thus driving parasite motility and host cell invasion. The minimal requirements for the TRAP binding to aldolase were scanned here and found to be shared by different human...

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Identifiers

PMID: 16278221
DOI: 10.1074/jbc.M506346200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Characterization of an aldolase-binding site in the Wiskott-Aldrich syndrome protein.PMID 16278221Read ↗

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