Article
Aldolase forms a bridge between cell surface adhesins and the actin cytoskeleton in apicomplexan parasites.
Molecular cell - 1 Apr 2003
Jewett Travis J, Sibley L David
Abstract excerpt
Host cell invasion by apicomplexan parasites requires coordinated interactions between cell surface adhesins and the parasite cytoskeleton. We have identified a complex of parasite proteins, including the actin binding protein aldolase, which specifically interacts with the C-terminal domains of several parasite adhesins belonging to the thrombospondin-related anonymous protein (TRAP) family. Binding of aldolase...
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