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Article

Role of Notch Signal Transduction in Kaposi's Sarcoma-Associated Herpesvirus Gene Expression

27 Oct 2005

Abstract excerpt

Kaposi's sarcoma-associated herpesvirus (KSHV) RTA transcription factor is recruited to its responsive elements through interaction with a Notch-mediated transcription factor, RBP-Jkappa, indicating that RTA mimics cellular Notch signal transduction to activate viral lytic gene expression. To test whether cellular Notch signal transduction and RTA are functionally exchangeable for viral gene expression, human...

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PMID: 16254371
DOI: 10.1128/jvi.79.22.14371-14382.2005

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Role of Notch Signal Transduction in Kaposi's Sarcoma-Associated Herpesvirus Gene ExpressionPMID 16254371Read ↗

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