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Article

Beyond apoptosis: nonapoptotic cell death in physiology and disease

1 Oct 2005

Abstract excerpt

Apoptosis is a morphologically defined form of programmed cell death (PCD) that is mediated by the activation of members of the caspase family. Analysis of death-receptor signaling in lymphocytes has revealed that caspase-dependent signaling pathways are also linked to cell death by nonapoptotic mechanisms, indicating that apoptosis is not the only form of PCD. Under physiological and pathological conditions,...

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PMID: 16234846
DOI: 10.1139/o05-065

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