Depolarization/repolarization, electrocardiographic abnormalities, and arrhythmias in cardiac channelopathies.

Abstract excerpt

Investigation of the etiology and pathogeneses of the genetic cardiac channelopathies has provided important insight into the mechanisms of ventricular arrhythmias. Some of these diseases are rare, such as the short QT-interval syndrome, but others such as the Brugada syndrome are the most common cause of unexplained sudden cardiac death in young men in Southeast Asia and Japan. Knowledge of the specific...

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