Article
[Gene organization of HLA and its association with ocular disease].
Nippon Ganka Gakkai zasshi - 1 Apr 1992
Mizuki N, Ohno S
Abstract excerpt
It is now evident that the human major histocompatibility complex (MHC), human leucocyte-associated antigen (HLA), regulates the immune response through discrimination between autologous and non autologous substances thereby displaying a high degree of genetic polymorphism. In recent years, the three-dimensional structure of HLA has been clarified by crystal analysis and provides the attractive hypothesis, the...
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