Article
A family based study of the genetic association between the PLA2G4D gene and schizophrenia.
Prostaglandins, leukotrienes, and essential fatty acids - 1 Dec 2005
Tao Ran, Yu Yaqin, Zhang Xiaojuan, Shi Jieping, Guo Yingjun, Wang Chunxiu, Han Baihui, Xu Qi, Shang Hong, Zhang Xuan, Xie Lin, Liu Shuzheng, Ju Guizhi, Shen Yan, Wei Jun
Abstract excerpt
The present study detected two single nucleotide polymorphisms (SNPs) at the PLA2G4D locus, rs2459692 and rs4924618, to investigate a genetic association between the PLA2G4D gene and schizophrenia. A total of 236 Chinese parent-offspring trios of Han descent were recruited for the genetic analysis. The transmission disequilibrium test (TDT) did not show allelic association either for rs2459692 (chi(2) = 0.217, P...
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