Article
ClpXP controls the expression of LEE genes in enterohaemorrhagic Escherichia coli.
FEMS microbiology letters - 1 Dec 2005
Tomoyasu Toshifumi, Takaya Akiko, Handa Yutaka, Karata Kiyonobu, Yamamoto Tomoko
Abstract excerpt
Enterohaemorrhagic Escherichia coli (EHEC) contains a 36-kb pathogenicity island termed the locus of enterocyte effacement (LEE), which encodes a type III secretion system (TTSS) and virulence proteins. In this paper, we show that the O157:H7 Sakai clpPX mutant strongly impaired the secretion of virulence proteins by TTSS and repressed transcription from all the LEE promoters. The rpoS mutation in O157:H7 Sakai...
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