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Article

Peptide pheromone induced cell death of<i>Streptococcus mutans</i>

30 Aug 2005

Abstract excerpt

Streptococcus mutans is considered one of the main causative agents of human dental caries. Cell-cell communication through two-component signal transduction systems (TCSTS) plays an important role in the pathogenesis of S. mutans. One of the S. mutans TCSTS, ComDE, controls both competence development and biofilm formation. In this study, we showed that addition of exogenous competence-stimulating peptide (CSP)...

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PMID: 16165324
DOI: 10.1016/j.femsle.2005.08.018

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