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Evaluation of mutagenic and genotoxic activities of new derivatives of anthracyclines.

Acta poloniae pharmaceutica - 1 Jan 2000

Chłopkiewicz Bozena, Ejchart Anna, Marczewska Jadwiga, Anuszewska Elzbieta, Priebe Waldemar

Abstract excerpt

The phenomenon of multidrug resistance is connected with an increased efflux of cytotoxic agents from the cells and is a serious problem in the treatment with anthracycline antibiotics. Search for new antitumor drugs from the anthracycline group are focused on the syntheris of derivatives with changes in saccharide and anthracycline parts. The genotoxic activity of selected nine new derivatives of anthracycline...

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PMID: 16161349

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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