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Article

The molecular basis of male sexual differentiation

1 Feb 2000

Abstract excerpt

Male sexual differentiation is the result of complex mechanisms involving developmental genetics and endocrinology. Formation of the bipotential gonads and subsequently the testes is dependent on a series of sex chromosome-linked and autosomal genes. The testes secrete both peptide and steroid hormones essential for the formation of internal and external genitalia. Hormone action is mediated via specific...

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PMID: 10664515
DOI: 10.1530/eje.0.1420101

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