Article
[Immunologic phenotype of lymphocytes in chronic B-cell lymphocytic leukemia. I. B- and T-lymphocytes in chronic lymphocytic leukemia].
Acta haematologica Polonica - 1 Jan 1992
Rupniewska Z M, Wach M, Kowal M, Roliński J, Antosz H
Abstract excerpt
This article contains the review and the critical discussion of studies of T and B lymphocytes in chronic B-cell lymphocytic leukaemia. It is not explicitly known now, which stage of differentiation of lympho-haemopoietic cells undergoes malignant transformation in CLL-B. Basing on VDJ recombination activity it is supposed that some cases derive from the stem cell, others--from B lineage cells.
Topics
- Antigens, CD
- Antigens, Differentiation, B-Lymphocyte
- B-Lymphocytes
- Cell Differentiation
- Chromosome Aberrations
- Genetic Markers
- Humans
- Leukemia, Lymphocytic, Chronic, B-Cell
- Phenotype
- T-Lymphocytes