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Article

Characterization of hMLH1 and hMSH2 Gene Dosage Alterations in Lynch Syndrome Patients

1 Sept 2005

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 16143124
DOI: 10.1053/j.gastro.2005.06.026

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Related research

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Research trail→

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Characterization of hMLH1 and hMSH2 Gene Dosage Alterations in Lynch Syndrome PatientsPMID 16143124Read ↗

Identification of new genetic alterations in MLH1, MSH2 and MSH6 using IHC and HRM analysis in Lynch syndrome-suspected patientsSemantic proximity Read ↗

Cancer Risks Associated With Germline Mutations in MLH1, MSH2, and MSH6 Genes in Lynch SyndromeSemantic proximity Read ↗

The role of the human DNA mismatch repair gene hMSH2 in DNA repair, cell cycle control and apoptosis: implications for pathogenesis, progression and therapy of cancerSemantic proximity Read ↗

Somatic Mutations in MLH1 and MSH2 Are a Frequent Cause of Mismatch-Repair Deficiency in Lynch Syndrome-Like TumorsSemantic proximity Read ↗

Methylation Analysis of MLH1 Improves the Selection of Patients for Genetic Testing in Lynch SyndromeSemantic proximity Read ↗

Epigenetic mechanisms in the pathogenesis of Lynch syndrome.Semantic proximity Read ↗

Patients with colorectal cancer associated with Lynch syndrome and MLH1 promoter hypermethylation have similar prognosesSemantic proximity Read ↗

Methylation Tolerance-Based Functional Assay to Assess Variants of Unknown Significance in the MLH1 and MSH2 Genes and Identify Patients With Lynch SyndromeSemantic proximity Read ↗

Lynch Syndrome GenesSemantic proximity Read ↗

Heritable epigenetic mutation of MLHI in a mother and daughter with Lynch syndromeSemantic proximity Read ↗

Msh2 deficiency leads to chromosomal abnormalities, centrosome amplification, and telomere capping defectSemantic proximity Read ↗

Roles of mismatch repair proteins hMSH2 and hMLH1 in the development of sporadic breast cancerSemantic proximity Read ↗

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