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Modulation of extracellular matrix genes reflects the magnitude of physiological adaptation to aerobic exercise training in humans

2 Sept 2005

Abstract excerpt

BACKGROUND: Regular exercise reduces cardiovascular and metabolic disease partly through improved aerobic fitness. The determinants of exercise-induced gains in aerobic fitness in humans are not known. We have demonstrated that over 500 genes are activated in response to endurance-exercise training, including modulation of muscle extracellular matrix (ECM) genes. Real-time quantitative PCR, which is essential for...

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PMID: 16138928
DOI: 10.1186/1741-7007-3-19

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