Article
High level of sequence diversity in the 16S rRNA genes of Haemophilus influenzae isolates is useful for molecular subtyping.
Journal of clinical microbiology - 1 Aug 2005
Sacchi Claudio T, Alber Dietmar, Dull Peter, Mothershed Elizabeth A, Whitney Anne M, Barnett Gwen A, Popovic Tanja, Mayer Leonard W
Abstract excerpt
A molecular typing method based on the 16S rRNA sequence diversity was developed for Haemophilus influenzae isolates. A total of 330 H. influenzae isolates were analyzed, representing a diverse collection of U.S. isolates. We found a high level of 16S rRNA sequence heterogeneity (up to 2.73%) and observed an exclusive correlation between 16S types and serotypes (a to f); no 16S type was found in more than one...
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