Article
Longitudinal changes in IQ among fragile X males: clinical evidence of more than one mutation?
American journal of medical genetics - 1 Jan 2000
Fisch G S, Shapiro L R, Simensen R, Schwartz C E, Fryns J P, Borghgraef M, Curfs L M, Howard-Peebles P N, Arinami T, Mavrou A
Abstract excerpt
Longitudinal changes in IQ among mentally retarded (MR) fragile X [fra(x)] males have been reported previously. While age is associated with decline in IQ, not all males are so affected. This suggests that there may be more than one subtype of affected fra(X) male. Therefore, we examined the dist...
Topics
- Adolescent
- Adult
- Aging
- Biometry
- Child
- Child, Preschool
- Fragile X Syndrome
- Humans
- Intelligence
- Male
- Mutation