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Article

Menopausal hormone therapy and irregular endometrial bleeding: a potential role for uterine natural killer cells?

The Journal of clinical endocrinology and metabolism - 1 Oct 2005

Hickey M, Crewe J, Goodridge J P, Witt C S, Fraser I S, Doherty D, Christiansen F T, Salamonsen L A

Abstract excerpt

CONTEXT: Irregular bleeding affects many users of combined menopausal hormone therapy (HT) and commonly leads to invasive and expensive investigations to exclude underlying malignancy. In most cases no abnormality is found. OBJECTIVE: The main objective of this study was to explore the role of uterine natural killer (uNK) cells and their regulatory cytokine IL-15 in irregular bleeding in HT users. DESIGN: This...

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Source

Identifiers

PMID: 16046584
DOI: 10.1210/jc.2005-0688

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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