Article
Genetics and psychopharmacology: prospects for individualized treatment.
Essential psychopharmacology - 1 Jan 2005
Nnadi Charles U, Goldberg Joseph F, Malhotra Anil K
Abstract excerpt
This article provides a clear and succinct description of the components of inheritance, such as trait transmission, genetic variability, and gene interaction. Genetic sequences constitute the prime focus of pharmacogenetic studies. Variations in drug-metabolizing enzyme systems tend to be monogenic, whereas the pharmacologic effects of medications appear to be polygenic, i.e., complex phenotypes shaped by the...
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