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Understanding and modulating ageing.

16 Sept 2005

Abstract excerpt

Ageing is characterized by a progressive accumulation of molecular damage in nucleic acids, proteins and lipids. The inefficiency and failure of maintenance, repair and turnover pathways is the main cause of age-related accumulation of damage. Research in molecular gerontology is aimed at understanding the genetic and epigenetic regulation of survival and maintenance mechanisms at the levels of transcription,...

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PMID: 16036613
DOI: 10.1080/15216540500092195

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