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Article

Glutathione-S-transferase M1, obesity, statins, and autonomic effects of particles: gene-by-drug-by-environment interaction.

American journal of respiratory and critical care medicine - 15 Dec 2005

Schwartz Joel, Park Sung Kyun, O'Neill Marie S, Vokonas Pantel S, Sparrow David, Weiss Scott, Kelsey Karl

Abstract excerpt

RATIONALE: Air pollution by particulate matter (PM) has been associated with cardiovascular deaths, although the mechanism of action is unclear. One proposed pathway is through disturbances of the autonomic control of the heart. OBJECTIVES: We tested the hypothesis that such disturbances are mediated by PM increasing oxidative stress by examining the association between PM and the high-frequency (HF) component of...

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Identifiers

PMID: 16020798
DOI: 10.1164/rccm.200412-1698OC
PMCID: PMC2718454

Genes

GSTM1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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