Nucleotide variation analysis does not support a causal role for plexin-A1 in hereditary congenital facial paresis.

doi:10.1016/j.devbrainres.2005.06.004

Article

Nucleotide variation analysis does not support a causal role for plexin-A1 in hereditary congenital facial paresis.

Brain research. Developmental brain research - 8 Aug 2005

van der Zwaag Bert, Burbach J Peter H, Brunner Han G, van Bokhoven Hans, Padberg George W

Abstract excerpt

Hereditary congenital facial paresis is a rare autosomal dominantly inherited disorder, in which pathological changes in the brainstem affect the paired facial nuclei and nerves. Previously, the neuropilin-1 protein has been shown to control axon guidance and cell body position of facial motor neurons, and mice with a targeted disruption of neuropilin-1 present with developmental defects of the facial nerve...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Nucleotide variation analysis does not support a causal role for plexin-A1 in hereditary congenital facial paresis.

Abstract excerpt

Topics

Related research