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Article

[Progress of study on sideroblastic anemia and its possible gene therapy--review].

Zhongguo shi yan xue ye xue za zhi - 1 Jun 2005

Wang Yi-Qun, Zhu Ping

Abstract excerpt

It was thought that delta-aminolevulinate synthase (ALAS) is the rate-limiting enzyme in the heme biosynthetic pathway. Actually there are two isozymes of ALAS and ALAS2 (erythroid delta-aminolevulinate synthase), they play the leading role in the hemoglobin biosynthetic pathway. Mutations in ALAS2 gene causes X-linked sideroblastic anemia (XLSA). About 25 different mutations in ALAS2 gene have been identified in...

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Share to 5-Aminolevulinate Synthetase
Share to Anemia, Sideroblastic
Share to Chromosomes, Human, X

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to ALAS2 gene

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Share to Genetic Therapy

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Source

Identifiers

PMID: 15972158

Genes

ALAS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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