[Study on the significance and application of crossover analysis in assessing gene-environmental interaction].

Abstract excerpt

OBJECTIVE: To examine the significance of crossover analysis in gene-environmental interaction studies. METHODS: Through elaboration of a case-control study on the increased risk of venous thrombosis in oral-conceptive users who were carriers of factor V Leiden mutation, core information from 2 x 4 crossover table were analyzed and compared with stratified analysis and 'case only' study. RESULTS: Different models...

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