Article
RNA viruses as complex adaptive systems.
Bio Systems - 1 Jul 2005
Elena Santiago F, Sanjuán Rafael
Abstract excerpt
RNA viruses have high mutation rates and so their populations exist as dynamic and complex mutant distributions. It has been consistently observed that when challenged with a new environment, viral populations adapt following hyperbolic-like kinetics: adaptation is initially very rapid, but then slows down as fitness reaches an asymptotic value. These adaptive dynamics have been explained in terms of populations...
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