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Article

Proteomic profiling of equine airway mucus reveals compositional changes in asthmatic phenotypes.

Scientific reports - 10 Feb 2026

Bartenschlager Florian, Kuropka Benno, Schmitz Philip, Dumke Fiona, Landmann Katharina, Gruber Achim D, Weise Christoph, Schnabel Christiane L, Gehlen Heidrun, Mundhenk Lars

Abstract excerpt

Mucus hypersecretion and accumulation are hallmark features of equine asthma (EA), a meaningful respiratory disorder in horses occurring in mild to moderate (MEA) and severe (SEA) forms. Changes of the proteomic composition of airway mucus in EA are poorly understood. Using label-free quantitative liquid chromatography-mass spectrometry, we analyzed airway mucus from SEA (n = 10), MEA (n = 6), and healthy (n = 8)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41667845
DOI: 10.1038/s41598-026-38766-3
PMCID: PMC12894910

Genes

SEA
MUC1
MUC4
MUC5AC
MUC5B

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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