Article
Group-beneficial traits, frequency-dependent selection and genotypic diversity: an antibiotic resistance paradigm.
Proceedings. Biological sciences - 7 Jan 2005
Dugatkin Lee Alan, Perlin Michael, Lucas J Scott, Atlas Ronald
Abstract excerpt
The evolution of group-beneficial traits potentially allows the survival of 'cheaters' that would otherwise be unfit. Here we describe experimental work on group-beneficial traits and the consequences of frequency-dependent selection in the context of bacterial antibiotic resistance. We constructed a 'self-limited antibiotic resistant' (SLAR) strain of Escherichia coli in which a TEM-1 beta-lactamase was anchored...
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