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Article

Is variation in the GABA(B) receptor 1 gene associated with temporal lobe epilepsy?

Epilepsia - 1 May 2005

Tan Nigel C K, Heron Sarah E, Scheffer Ingrid E, Berkovic Samuel F, Mulley John C

Abstract excerpt

PURPOSE: gamma-Aminobutyric acid (GABA)-receptor genes are prime candidates for a role in seizure susceptibility. An association between the c.1465G-->A variant in the GABA(B) receptor 1 gene (GABBR1) and susceptibility to temporal lobe epilepsy (TLE) has been reported in an Italian cohort. We sought to replicate this association in an independent Australian cohort. METHODS: The 234 patients with TLE and 164...

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Source

Identifiers

PMID: 15857448
DOI: 10.1111/j.1528-1167.2005.49004.x

Genes

GABBR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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