Article
Distribution of Helicobacter pylori cagA, cagE and vacA in different ethnic groups in Kuala Lumpur, Malaysia.
Journal of gastroenterology and hepatology - 1 Apr 2005
Tan Huck Joo, Rizal Abdul Manaf, Rosmadi Mohamed-Yusoff, Goh Khean-Lee
Abstract excerpt
BACKGROUND AND AIMS: There is a geographic variation in Helicobacter pylori (HP) genotypes and virulence factors. Cytotoxin associated genes A (cagA) and E (cagE), and certain vacuolating cytotoxin (vacA) genotypes are associated with peptic ulcer disease (PUD). There is also a different prevalence of PUD among different ethnic groups in Malaysia. The present study compared the distribution of vacA alleles and...
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