Distribution of Helicobacter pylori cagA, cagE and vacA in different ethnic groups in Kuala Lumpur, Malaysia.

doi:10.1111/j.1440-1746.2005.03783.x

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Article

Distribution of Helicobacter pylori cagA, cagE and vacA in different ethnic groups in Kuala Lumpur, Malaysia.

Journal of gastroenterology and hepatology - 1 Apr 2005

Tan Huck Joo, Rizal Abdul Manaf, Rosmadi Mohamed-Yusoff, Goh Khean-Lee

Abstract excerpt

BACKGROUND AND AIMS: There is a geographic variation in Helicobacter pylori (HP) genotypes and virulence factors. Cytotoxin associated genes A (cagA) and E (cagE), and certain vacuolating cytotoxin (vacA) genotypes are associated with peptic ulcer disease (PUD). There is also a different prevalence of PUD among different ethnic groups in Malaysia. The present study compared the distribution of vacA alleles and...

Topics

Alleles
Antigens, Bacterial
Bacterial Proteins
China
Female
Genes, Bacterial
Genotype
Helicobacter Infections
Helicobacter pylori
Humans
India
Malaysia
Male
Middle Aged
Peptic Ulcer
Prospective Studies
Virulence

Source

Open in PubMed

Identifiers

PMID: 15836708
DOI: 10.1111/j.1440-1746.2005.03783.x

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