Article
Toward a neutral evolutionary model of gene expression.
Genetics - 1 Jun 2005
Khaitovich Philipp, Pääbo Svante, Weiss Gunter
Abstract excerpt
We introduce a stochastic model that describes neutral changes of gene expression over evolutionary time as a compound Poisson process where evolutionary events cause changes of expression level according to a given probability distribution. The model produces simple estimators for model parameters and allows discrimination between symmetric and asymmetric distributions of evolutionary expression changes along an...
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