Article
Association between the neuron-specific RNA-binding protein ELAVL4 and Parkinson disease.
Human genetics - 1 Jun 2005
Noureddine Maher A, Qin Xue-Jun, Oliveira Sofia A, Skelly Tara J, van der Walt Joelle, Hauser Michael A, Pericak-Vance Margaret A, Vance Jeffery M, Li Yi-Ju
Abstract excerpt
Inflammatory processes have been implicated in the cascade of events that lead to nerve cell death. In the nervous system, a number of genes involved in inflammation pathways are regulated post-transcriptionally via the interaction of their mRNAs with specific RNA-binding Hu proteins, the vertebrate homologues of the Drosophila ELAV (for embryonic lethal abnormal vision). The gene encoding ELAVL4, a member of the...
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