Article
Phenotype switching affects biofilm formation by Candida parapsilosis.
Microbiology (Reading, England) - 1 Apr 2005
Laffey Sean F, Butler Geraldine
Abstract excerpt
Generation of biofilms by the pathogenic yeast Candida parapsilosis is correlated closely with disease. The phenomenon of phenotype switching in 20 isolates of C. parapsilosis was examined and the relationship with biofilm development was investigated. Four stable and heritable phenotypes were identified--crepe, concentric, smooth and crater. Cells from crepe and concentric phenotypes are almost entirely...
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