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Article

Mumps virus V protein antagonizes interferon without the complete degradation of STAT1.

Journal of virology - 1 Apr 2005

Kubota Toru, Yokosawa Noriko, Yokota Shin-Ichi, Fujii Nobuhiro, Tashiro Masato, Kato Atsushi

Abstract excerpt

Mumps virus (MuV) has been shown to antagonize the antiviral effects of interferon (IFN) through proteasome-mediated complete degradation of STAT1 by using the viral V protein (T. Kubota et al., Biochem. Biophys. Res. Commun. 283:255-259, 2001). However, we found that MuV could inhibit IFN signaling and the generation of a subsequent antiviral state long before the complete degradation of cellular STAT1 in...

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Source

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Identifiers

PMID: 15767445
DOI: 10.1128/JVI.79.7.4451-4459.2005
PMCID: PMC1061565

Genes

STAT1
STAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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