Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Activation of a phytopathogenic bacterial effector protein by a eukaryotic cyclophilin.

Science (New York, N.Y.) - 22 Apr 2005

Coaker Gitta, Falick Arnold, Staskawicz Brian

Abstract excerpt

Innate immunity in higher plants invokes a sophisticated surveillance system capable of recognizing bacterial effector proteins. In Arabidopsis, resistance to infection by strains of Pseudomonas syringae expressing the effector AvrRpt2 requires the plant resistance protein RPS2. AvrRpt2 was identified as a putative cysteine protease that results in the elimination of the Arabidopsis protein RIN4. RIN4 cleavage...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cyclophilins
Share to Cyclosporine
Share to Cysteine Endopeptidases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Enzyme Activation

Share to Mass Spectrometry

Share to Peptide Mapping

Share to Pseudomonas syringae

Share to Sirolimus

Source

Identifiers

PMID: 15746386
DOI: 10.1126/science.1108633

Genes

RPS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Activation of a phytopathogenic bacterial effector protein by a eukaryotic cyclophilin.PMID 15746386Read ↗

Eukaryotic cyclophilin as a molecular switch for effector activation.Semantic proximity Read ↗

Initiation of RPS2-specified disease resistance in Arabidopsis is coupled to the AvrRpt2-directed elimination of RIN4.Semantic proximity Read ↗

The Pseudomonas syringae type III effector AvrRpt2 promotes pathogen virulence via stimulating Arabidopsis auxin/indole acetic acid protein turnover.Semantic proximity Read ↗

Arabidopsis RIN4 is a target of the type III virulence effector AvrRpt2 and modulates RPS2-mediated resistance.Semantic proximity Read ↗

The A. thaliana disease resistance gene RPS2 encodes a protein containing a nucleotide-binding site and leucine-rich repeats.Semantic proximity Read ↗

The Bacterial Effector AvrB-Induced RIN4 Hyperphosphorylation Is Mediated by a Receptor-Like Cytoplasmic Kinase Complex in Arabidopsis.Semantic proximity Read ↗

RPS2 of Arabidopsis thaliana: a leucine-rich repeat class of plant disease resistance genes.Semantic proximity Read ↗

A bacterial virulence protein suppresses host innate immunity to cause plant disease.Semantic proximity Read ↗

A bacterial E3 ubiquitin ligase targets a host protein kinase to disrupt plant immunity.Semantic proximity Read ↗

The targeting of plant cellular systems by injected type III effector proteins.Semantic proximity Read ↗

Molecular basis for the RIN4 negative regulation of RPS2 disease resistance.Semantic proximity Read ↗

Cleavage of Arabidopsis PBS1 by a bacterial type III effector.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.