Article
Anticancer activity of bacteriophage T4 and its mutant HAP1 in mouse experimental tumour models.
Anticancer research - 1 Jan 2000
Dabrowska Krystyna, Opolski Adam, Wietrzyk Joanna, Switala-Jelen Kinga, Godlewska Joanna, Boratynski Janusz, Syper Danuta, Weber-Dabrowska Beata, Gorski Andrzej
Abstract excerpt
BACKGROUND: Previously, we have shown the ability of the bacteriophage T4 and its substrain HAP1 (selected for a higher affinity to melanoma cells) to reveal antimetastatic activity in a mouse melanoma model. Here, we investigated the potential phage anticancer activity in primary tumour models. MATERIALS AND METHODS: Mice were inoculated subcutaneously with B16 or LLC cells (collected from in vitro culture)....
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