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Article

Signaling Networks in Cutaneous Melanoma Metastasis Identified by Complementary DNA Microarrays

1 Feb 2005

Abstract excerpt

BACKGROUND: Melanoma is a complex multigenic disease, susceptibility to which is determined by several parallel and stepwise progressive pathways affecting growth control, differentiation, cell adhesion, and survival. Melanoma and human cancers in general undergo a continuous development from benign to malignant states, as most thoroughly documented in the multistep mole-to-melanoma transition. OBJECTIVE: To...

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PMID: 15724012
DOI: 10.1001/archderm.141.2.165

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