Article
T-cell-depleted CD34+ cell transplantation from an HLA-mismatched donor in a low-birthweight infant with X-linked severe combined immunodeficiency.
Journal of pediatric hematology/oncology - 1 Feb 2005
Nomura Akihiko, Takada Hidetoshi, Ohga Shouichi, Ishii Naoto, Inoue Toshiro, Hara Toshiro
Abstract excerpt
The best strategy of hematopoietic stem cell (HSC) transplantation for low-birthweight (LBW) infants with severe combined immunodeficiency (SCID) remains to be determined. To avoid the toxicity of drugs used for the transplantation and the risk of graft-versus-host disease (GVHD), the authors performed allogeneic bone marrow HSC transplantation with a combination of CD34 selection and T-cell depletion in a LBW...
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