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Article

Evaluation of 45S5 bioactive glass combined as a bone substitute in the reconstruction of critical size calvarial defects in rabbits.

The Journal of craniofacial surgery - 1 Jan 2005

Moreira-Gonzalez Andrea, Lobocki Catherine, Barakat Khaled, Andrus Lee, Bradford Melinda, Gilsdorf Milessa, Jackson Ian T

Abstract excerpt

Biomaterial research and tissue engineering have guided new developments in bone replacement. In this study, the osteoconductive and osteoinductive properties of 45S5 Bioglass (Novabone-C/M, Porex Surg., Newnan, GA), granules as a bone replacement material for large calvarial defects were evaluated. Rabbit periosteal cells were expanded in culture and used in vivo. Alkaline-phosphatase assay, collagen type I, and...

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Identifiers

PMID: 15699647
DOI: 10.1097/00001665-200501000-00013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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