Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phenotypical and functional differences in germinative subpopulations derived from normal and psoriatic epidermis.

The Journal of investigative dermatology - 1 Feb 2005

Franssen Manon E J, Zeeuwen Patrick L J M, Vierwinden Gerty, van de Kerkhof Peter C M, Schalkwijk Joost, van Erp Piet E J

Abstract excerpt

A model that explains how maintenance of normal homeostasis in human epidermis is achieved describes a heterogeneous cell population of stem cells (SC) and transit amplifying cells (TAC). There must be a tightly regulated balance between SC self-renewal and the generation of TAC that undergo a limited number of divisions before giving rise to postmitotic, terminally differentiated cells. To investigate whether...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biopsy
Share to Cell Division

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epidermis

Share to Flow Cytometry

Share to Integrin beta1

Share to Keratinocytes

Share to Ki-67 Antigen

Share to Psoriasis

Source

Identifiers

PMID: 15675957
DOI: 10.1111/j.0022-202X.2004.23612.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phenotypical and functional differences in germinative subpopulations derived from normal and psoriatic epidermis.PMID 15675957Read ↗

Functional Characterization of Quiescent Keratinocyte Stem Cells and Their Progeny Reveals a Hierarchical Organization in Human Skin EpidermisSemantic proximity Read ↗

Flow cytometric identification of proliferative subpopulations within normal human epidermis and the localization of the primary hyperproliferative population in psoriasis.Semantic proximity Read ↗

Identification and isolation of candidate human keratinocyte stem cells based on cell surface phenotypeSemantic proximity Read ↗

Isolation and In Vitro Characterization of Epidermal Stem Cells.Semantic proximity Read ↗

Location and phenotype of human adult keratinocyte stem cells of the skin.Semantic proximity Read ↗

Induction of normal and psoriatic phenotypes in submerged keratinocyte cultures.Semantic proximity Read ↗

Separation of human epidermal stem cells from transit amplifying cells on the basis of differences in integrin function and expressionSemantic proximity Read ↗

Epidermal kinetic alterations required to generate the psoriatic phenotype: a reappraisal.Semantic proximity Read ↗

Stem cells in psoriasis.Semantic proximity Read ↗

Characterizing the phenotype of murine epidermal progenitor cells: complementary whole-mount visualization and flow cytometry strategies.Semantic proximity Read ↗

Single-cell expression profiling of human epidermal stem and transit-amplifying cells: Lrig1 is a regulator of stem cell quiescenceSemantic proximity Read ↗

Extensive tissue-regenerative capacity of neonatal human keratinocyte stem cells and their progenySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.