Article
Does genotype mask the relationship between psychological factors and immune function?
Brain, behavior, and immunity - 1 Mar 2005
Smith Alison, Vollmer-Conna Ute, Geczy Andrew, Dunckley Heather, Bennett Barbara, Hickie Ian, Lloyd Andrew
Abstract excerpt
This paper examined the interaction between genetic influences of the polymorphic human leukocyte antigens (DRB1 and DQB1) and psychological distress on the development of cellular immunity to the novel antigen, keyhole limpet hemocyanin (KLH). Participants (n = 227) were immunized with KLH and the development of cutaneous delayed-type hypersensitivity (DTH) against KLH was examined 3 weeks later. Distress was...
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