Article
A new arginine substitution mutation of DSRAD gene in a Chinese family with dyschromatosis symmetrica hereditaria.
Journal of dermatological science - 1 Feb 2005
Li Cheng-Rang, Li Ming, Ma Hui-Jun, Luo Dan, Yang Li-Jia, Wang Da-Guang, Zhu Xiao-Hong, Yue Xue-Zhuang, Chen Wen-Qi, Zhu Wen-Yuan
Abstract excerpt
BACKGROUND: Dyschromatosis symmetrica hereditaria (DSH) is a pigmentary genodermatosis of autosomal dominant inheritance characterized by a mixture of hyperpigmented and hypopigmented macules distributed on the dorsal aspects of the hands and feet. To date, only three articles testified that DSH is caused by the mutations of DSRAD gene (also called ADAR1) encoding for RNA-specific adenosine deaminase. OBJECTIVE:...
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