Article
Haplotype analysis of carnitine transporters and left ventricular mass in human essential hypertension.
Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation - 1 Jan 2005
Tripodi Grazia, Modica Rossana, Stella Alessandra, Bigatti Giada, Bianchi Giuseppe, Stella Paola
Abstract excerpt
OBJECTIVE: The carnitine-associated alteration of myocardial fatty acid metabolism may be one of the molecular mechanisms underlying left ventricular hypertrophy (LVH) in essential hypertension. We tested the hypothesis that polymorphisms of the genes involved in carnitine transport, OCTN2, CPT1A, CPT1B, and CPT2, might be associated with LVH. DESIGN: Haplotype-based association analysis in an observational...
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