Article
Mycobacterium tuberculosis molecular evolution in western Mediterranean Islands of Sicily and Sardinia.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Mar 2005
Sola Christophe, Ferdinand Séverine, Sechi Leonardo A, Zanetti Stefania, Martial Dominique, Mammina Caterina, Nastasi Antonino, Fadda Giovanni, Rastogi Nalin
Abstract excerpt
In this study, a total of 204 Mycobacterium tuberculosis DNAs from Sicily (n = 144) and Sardinia (n = 60) were studied by three genotyping methods. Results were analyzed both within and across islands, to define the phylogeographical specificities of the genotypes, look for their diversity and infer a molecular evolutionary scenario. A strong link between geography and tuberculosis genotypes was observed in...
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