Article
[A probability analysis for HLA matching in adult stem cell transplantation treating nervous genetic diseases].
Zhongguo shi yan xue ye xue za zhi - 1 Dec 2004
Xiao Lu-Lu, Chen Wei, Zhang Cheng, Liu Zhuo-Lin, Ye Xin, Zhang Wei-Dong, Yi Yan
Abstract excerpt
The aim of this study was to investigate the clinical feasibility of adult stem cell transplantation for lethal mono-gene inherited disease, Duchenne muscular dystrophy (DMD). A total of 30 blood samples from DMD patients were genotyped with HLA-A,-B and -DR alleles by means of polymerase chain reaction-reverse sequence specific oligonucleotide (PCR-RSSO). The HLA gene types in 30 DMD patients were compared with...
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