Article
Nonassociation of interleukin 4 intron 3 and 590 promoter polymorphisms with bronchopulmonary dysplasia for ventilated preterm infants.
Biology of the neonate - 1 Jan 2005
Lin Hung-Chih, Su Bai-Horng, Chang Jeng-Sheng, Hsu Chin-Moo, Tsai Chang-Hai, Tsai Fuu-Jen
Abstract excerpt
Interleukin 4 (IL-4) stimulates and amplifies the inflammatory response, stimulates collagen synthesis in fibroblasts, promotes the progression to fibrosis and has been shown to inhibit the production of several inflammatory cytokines in the development of bronchopulmonary dysplasia (BPD) and airway hyperreactivity. We aimed to investigate whether IL-4 polymorphisms in ventilated preterm infants were associated...
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