Article
Analysis of Campylobacter jejuni capsular loci reveals multiple mechanisms for the generation of structural diversity and the ability to form complex heptoses.
Molecular microbiology - 1 Jan 2005
Karlyshev Andrey V, Champion Olivia L, Churcher Carol, Brisson Jean-Robert, Jarrell Harold C, Gilbert Michel, Brochu Denis, St Michael Frank, Li Jianjun, Wakarchuk Warren W, Goodhead Ian, Sanders Mandy, Stevens Kim, White Brian, Parkhill Julian, Wren Brendan W, Szymanski Christine M
Abstract excerpt
We recently demonstrated that Campylobacter jejuni produces a capsular polysaccharide (CPS) that is the major antigenic component of the classical Penner serotyping system distinguishing Campylobacter into >60 groups. Although the wide variety of C. jejuni serotypes are suggestive of structural differences in CPS, the genetic mechanisms of such differences are unknown. In this study we sequenced biosynthetic cps...
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